Ajibade A FWACS, Olaitan PB FWACS

Available online Jul 18, 2018.

[ Original ] Volume 23, Issue 2, 2014, Pages 142-148


BACKGROUND: In Nigeria, nurse-anaesthetists are responsible for administering perioperative prophylactic
antibiotics in a large number of operations but this practice is poorly studied.
AIMS: The aim of this study was to evaluate the knowledge, attitude and practice of perioperative antibiotic
prophylaxis among nurse-anaesthetists in Nigeria.
METHODS: A cross-sectional study was conducted among nurse-anaesthetists at an Annual General
Meeting/Scientific Conference of Nigeria Association of Nurse-Anaesthetists, using a pre-tested questionnaire.
RESULTS: Of 70 questionnaires, 67 were returned. Antibiotic administration at induction of anaesthesia was
considered inappropriate by 79.1% (n=67) and safe by 42.6% (n=61). There was poor knowledge of indications
for intraoperative administration. There was agreement by 81.9% of respondents that anaesthetists should
administer prophylactic antibiotics (n=66) but 72.2% would want the surgeon to indicate the time of
administration (n=60). About 69.3% and 77.2% of respondents administered prophylactic antibiotics before
tourniquet application (n=62) and skin incision (n=66) respectively in their practice but the latter finding was not
corroborated by internal validity check. Availability of a hospital perioperative antibiotic prophylaxis protocol
(p=0.048) and practice for 10 or more years (p=0.009) were associated with higher knowledge score.
CONCLUSION: Inclusion of lectures on perioperative antibiotic prophylaxis in nurse-anaesthesia training
curriculum, having hospital perioperative antibiotic prophylaxis protocol, stating in the protocols that surgeons
give instructions on timing of antibiotic administration and ensuring adherence to the protocols may improve
knowledge and practice of perioperative antibiotic prophylaxis among nurse-anaesthetists.


Antibiotics, antibiotic prophylaxis, surgical wound infection, anaesthesia,

April - June 2014

Volume 23 | Issue 2

Page Nos. 142-148

Online since Jul 13, 2018

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