Available online Jul 19, 2018.
[ Original ] Volume 23, Issue 2, 2014, Pages 149-152
Preterm delivery is associated with low birth weight of
babies (birth weight < 2,500g). The low birth weights
may be appropriate or inappropriate for gestational
age. Many factors have been associated with preterm
Our objective was to evaluate the placental histopathology in low birth weight
infants(LBW birth weight<2500g) and to determine if placental Histopathological finding are associated with low birth weight and parttern delivers
The total number of LBW births seen was 38. The
Male: Female ratio was 1.8:1. The maternal age range
was from 19 to 38 years (mean age = 28.7yrs ±
5.37SD). The parity ranges from 0 to 5. The birth
weight ranged 0.75 to 2.4kg (mean 1.84kg ±0.39SD).
The gestational age at delivery range was 25 to
38weeks (mean 32.85 weeks ±3.7SD) . The placenta
weight ranged from 0.4 to 1.8. (Mean 0.69kg ± 0.34
SD) .Table showed summary of patients parameters.
Histological examination of the placentae showed that
17 cases (44.7%) had evidence of placenta malaria, 17
cases(44.7%) had chorioamnionitis, 9 cases (23.7%)
had villitis, 2 cases (5.3%) had vasculitis and 4cases
(10.5%) had no abnormality. Table 2 showed
frequency and proportion of histological
Four sets of twins (8 cases) were among the 38 cases
The placenta of thirty-eight consecutive cases of
LBW deliveries at the Obafemi Awolowo University Teaching Hospital, Wesley Guild Hospital, Ilesa, Osun
state South-Western Nigeria were histologically
examined. Data on the birth weight of the baby,
placental weight, parity of mother, age of the mother,
gestational age at delivery of the baby and outcome of
management was obtained for each case.
Conclusion: The main placenta findings in LBW babies
include chorioamnionitis and placenta malaria
infection. These factors are known contributory
factors to preterm labour. Other factors include
multiple gestation and abruptio placenta. Improved
maternity care, health education of pregnant women
and use of intermittent preventive treatment for
malaria in pregnancy will go a long way in improving
outcome of pregnancy.
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Volume 23 | Issue 2
Page Nos. 149-152
Online since Jul 13, 2018