CRYSTALLOID PRELOAD SHOWS TRANSIENT SUPERIORITY OVER COLLOID, OR THEIR COMBINATION IN SPINAL ANAESTHESIA - INDUCED HYPOTENSION PROPHYLAXIS FOR CAESAREAN SECTION

Idehen Hanson Osazuwa , Amadasun Ebague

Available online Jul 19, 2018.

[ Original ] Volume 24, Issue 2, 2015, Pages 137-143


Abstract

BACKGROUND
Many studies comparing different intravenous fluid types usually do not use equipotent volumes of 3:1 crystalloid: colloid ratio in such
comparisons. Conflicting results emanate from such studies.This study was designed to compare the efficacy of equipotent volumes of
crystalloid,colloid and combination of crystalloid/colloid in spinal anaesthesia- induced hypotension prophylaxis.
METHODOLOGY
Pregnant women scheduled for elective Caesarean section were prospectively randomized to three groups to each received either
1500ml of Ringers lactate, or 500 ml of 6% pentastarch or a combination of 250 ml of 6% pentastarch and 750 ml of Ringers lactate
intravenous fluid preload,before spinal anaesthesia.Hemodynamic variables were monitored.
RESULTS
First 10minutes, crystalloid showed better efficacy in hypotension prophylaxis over the other regimen. In the next 30 minutes however,
there were no significant differences between the groups.
CONCLUSION
Crystalloids proved more effective than colloid or their combination in hypotension prophylaxis in the first 10minutes after spinal
anaesthesia.


Keywords

Spinal anaesthesia, Caesarean section, hypotension, intravenous fluids.,