Available online Jul 19, 2018.
[ Original ] Volume 24, Issue 3, 2015, Pages 256-260
BACKGROUND:Occupational exposure to petroleum products is known to be associated with a number of
health risks as well as adverse effects on haematological indices.
OBJECTIVE: To evaluate the effect of exposure to petroleum products on haematological parameters in
automobile mechanics in Nnewi,south-east Nigeria.
SUBJECTS AND METHODS: Fifty (50) automobile technicians and 50 healthy controls participated in the
study. Full blood count was performed for each participant using the automated Sysmex haemocytometer (Model
PCE 210) while data analysis was done using the SPSS (statistical package for social sciences) version 16 computer
soft ware (Chicago, IL, Inc.). Results were expressed as frequencies,means and standard deviations;comparison of
haematological parameters was made between subjects and controls and at different durations of exposure using
the students't-test and analysis of variance (ANOVA), respectively. The level of statistical significance was p<0.05
(at 95% CI).
Ethical approval was obtained from the Institutional review board and all participants gave informed consent.
RESULTS: There red blood cell count (RBC) and haematocrit were significantly lower while the platelet count
was significantly higher in test subjects compared with controls (p values; 0.04, 0.03 and 0.01, respectively).
Correspondingly, the mean cell volume (MCV) and mean cell haemoglobin (MCH) were significantly lower in test
subjects compared with controls (p=0.02 and 0.03, respectively).The red cell count, MCV and platelet count
significantly decreased with increasing duration of work exposure (p=0.001,respectively).
CONCLUSION:Occupational exposure to petroleum products adversely affects blood counts,with a significant
decrease in RBC,MCV and platelet count as duration of exposure increases.
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Volume 24 | Issue 3
Page Nos. 256-260
Online since Jul 12, 2018