Available online Jul 13, 2018.
[ Original ] Volume 19, Issue 4, 2010, Pages 451-454
Background: Gastric cancer believed to be rare in the
past in Africa, is now one of the leading cancer
morbidity and mortality. It is now known gastric cancer
is 2-3 times higher in males than females living in the
same environment. We aim to describe the
comprehensive histological characteristics of gastric
cancer with age and sex distribution.
Methods: The study site was Jos University Teaching
Hospital situated in the capital of Plateau State. The
hospital has a bed capacity of 530. The study materials
were obtained from all stained specimens of gastric
cancer recorded in the histopathology laboratory of the
teaching hospital between 1985 to 2004. The biopsy
site was noted. These were divided into the following
groups: Cardia, body and an thrum/pyloric regions
respectively. Or the information included age and sex
of the patients.
Results: There were a total of 205 gastric cancer
histological confirmed, out of 5705 malignant tumours
recorded in the same period. There were a total of 145
cases in male and 60 in females giving a male: female
ratio 2.4:1. The highest frequencies of gastric cancers
were located in the anthral and cardia regions which
accounted for 79% of all the tumours. Well
differentiated adenocarcinoma (intestinal type) was the
most frequent histological subtypes 51.2%), this was
followed by poorly and diffusely infiltrating carcinoma.
Other cancers included signet ring carcinoma, Non-
Hodgkin's lymphoma and leiomyosarcoma in that
order. The study has also demonstrated H pylori at the
background of intestinal type adenocarcinoma which
was seen in the body and an thrum.
Conclusion: The study has shown that gastric cancer
is not only common but it occur more males than
females. The high proportion of H pylori in our
environment might indicate a possible aetiological
association. Therefore eradication of H pylori might
reduce the prevalence of gastric carcinoma.
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Volume 19 | Issue 4
Page Nos. 451-454
Online since Jul 13, 2018